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Patients are now the real guinea pigs

Antidote Europe welcomes recent French media reports warning the public about dangerous medicines.

BBC presenter Uhlenbroek joins scientists on campaign

The campaign’s report presents an immediate science strategy to end poisoning tests on non-human primates.

Making a molehill out of the Bisphenol A mountain

Antidote Europe has criticised the French government for taking very timid measures to ban the synthetic chemical bisphenol A (BPA). It makes no sense to protect nursing infants by banning the substance in baby bottles when their mothers are exposed to it on a daily basis — not to mention the effect on the foetuses of pregnant women.

Another warning about bisphenol A

Antidote Europe has re-issued its warning on bisphenol A, criticizing the French Food Safety Agency (AFSSA) on its confused and unclear public announcements regarding this chemical.

Antidote Europe receives achievement award

Antidote Europe was awarded the Pietro Croce prize.

Is Bisphenol A the new silent killer?

Antidote Europe has launched a public campaign regarding the dangers of bisphenol A and has duly informed the new president of the European Parliament.

Bisphenol A, a chemical time bomb?

It is difficult to understand why food safety agencies continue to place their trust in ambiguous animal data when human data is readily available. The fact that DES and BPA share striking similarities in their structures is extremely worrisome and lends weight to the possibility that BPA is a “chemical time bomb” in terms of our health.

EU directive lags woefully behind the science

With a crucial vote about to take place on Tuesday 31st March, by the Agriculture Committee (AGRI) of the European Parliament, Antidote Europe has written to all members of this committee, urging them to include a clause in the revised version of the 86/609 directive, to facilitate the adoption of any scientifically sound, non animal method, based on the “weight of evidence” principle. Such a clause would significantly increase the scope and application of non animal methods in practice.

EU continues to allow bisphenol in baby dummies

According to EFSA, the exposure of the human foetus to bisphenol A would be negligible because the mother rapidly metabolizes and eliminates this substance from her body. This conclusion is in contradiction with basic pharmacokinetics knowledge.

EU cautioned not to use animal organs

Antidote Europe has issued an urgent caution against the idea of transplanting animal organs into people.

 

Press Releases

Antidote Europe’s expert contribution recognised

 

Date

Mon 25 Jun 2007

 

Summary

Test results obtained by Antidote Europe based on the toxicogenomic evaluation of 22 chemical substances are now registered on an international database, which is a very positive sign indeed.

Results of a study by Antidote Europe on harmful chemicals have now been registered on an official website. Twenty-two of the 28 substances tested, among them ingredients found in pesticides and cosmetics, have now been logged in the prestigious MIAME (Minimum Information About a Microarray Experiment) database. This is a major boost to the use of toxicogenomics in the field of toxicity testing. Toxicogenomics — the study of how genes respond to environmental stress and toxic substances — is now increasingly being seen as a scientifically sound non-animal method of yielding data on the deleterious effects that chemicals may have on human health and the environment.

This latest development is especially relevant to the new EU chemicals directive (REACH), which entered into force on 1st June 2007 and which calls for animal testing on a massive scale. The advantages of toxicogenomics, in terms of its relevance to human health, overall cost and time saving benefits, points to animal experiments as being “bad science” — a term used to describe animal tests by a senior scientist within the European Commission.

Notes to editors:

1. MIAME reference numbers: E-TOXM-31 and A-MEXP-798
2. REACH (registration, evaluation and authorisation of chemicals - Directive 2006/121/EC)
4. Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has been the lack of standards for presenting and exchanging such data. The Minimum Information About a Microarray Experiment (MIAME), describes the minimum information required to ensure that microarray data can be easily interpreted and that results derived from its analysis can be independently verified. The ultimate goal of this work is to establish a standard for recording and reporting microarray-based gene expression data, which will in turn facilitate the establishment of databases and public repositories and enable the development of data analysis tools (ref. Nature Genetics 29, 365 - 371 (2001) doi:10.1038/ng1201-365)

 

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