ccc Patients are now the real guinea pigs | Antidote Europe

More Press Releases

Scientists question value of monkey experiments

An article published in the peer-reviewed Medicolegal and Bioethics presents a rare challenge not just to the ethics but also to the science of using non human primates in research.

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Another warning about bisphenol A

Antidote Europe has re-issued its warning on bisphenol A, criticizing the French Food Safety Agency (AFSSA) on its confused and unclear public announcements regarding this chemical.

Antidote Europe receives achievement award

Antidote Europe was awarded the Pietro Croce prize.

Is Bisphenol A the new silent killer?

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Bisphenol A, a chemical time bomb?

It is difficult to understand why food safety agencies continue to place their trust in ambiguous animal data when human data is readily available. The fact that DES and BPA share striking similarities in their structures is extremely worrisome and lends weight to the possibility that BPA is a “chemical time bomb” in terms of our health.

EU directive lags woefully behind the science

With a crucial vote about to take place on Tuesday 31st March, by the Agriculture Committee (AGRI) of the European Parliament, Antidote Europe has written to all members of this committee, urging them to include a clause in the revised version of the 86/609 directive, to facilitate the adoption of any scientifically sound, non animal method, based on the “weight of evidence” principle. Such a clause would significantly increase the scope and application of non animal methods in practice.


Press Releases

Patients are now the real guinea pigs



Thu 6 Jan 2011



Antidote Europe welcomes recent French media reports warning the public about dangerous medicines.


Antidote Europe welcomes recent media reports warning the public about dangerous medicines (the latest are the drugs mediator and buflomedil). The French-based NGO fully endorses this latest expose that reveals the enormous gulf between reliable scientific methods and some of the currently used tests, which are hopelessly out of date.

All medical drugs are required to undergo extensive animal testing, even though animals cannot reliably predict what will happen in a human. This message was clearly brought home by the near fatal Northwick Park clinical trial involving six young men who received an experimental drug at one five-hundredth the dose found safe in monkeys. While cases like this are relatively rare, the rate of adverse drug reactions in the general population is far greater. In fact, nine out of ten drugs that pass animal tests fail to make it through clinical trials involving people (1). This begs the question of why our regulatory authorities still require animal tests. Rather than protecting the public it seems that animal tests actually allow many toxic products to slip through the safety net and reach the market. As a result, about 20,000 people die of adverse drug reactions in France every year (2), making adverse drug reactions the fourth leading cause of death.

The regulatory authorities must bear the major responsibility for the current situation, at a time when modern scientific methods are available, including such techniques as toxicogenomics and human DNA studies — see The use of such techniques could prevent further drug tragedies. The use of human DNA brings us ever closer to the application of “personalised medicine”, where drugs are tailor-made to suit the individual, thus reducing the risk of an adverse reaction. When it comes to the safety testing of drugs and other chemicals, people clearly are not 70kg rats.

(1) Lester Crawford deputy commissioner FDA, quoted in The Scientist (6.8.2004) “Innovation or Stagnation, Challenge and Opportunity on the Critical Path to new Medical Products”.
(2) Le Monde, 13 November 1997, quote by Bernard Kouchner, secretary of state for health.


Publication Date

Thu 6 Jan 2011



André Ménache
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Claude Reiss
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